A father (Michael Shannon) goes on the run to protect his young son, Alton (Jaeden Lieberher), and uncover the truth behind the boy's special powers. What starts as a race from religious extremists and local law enforcement quickly escalates to a nationwide manhunt involving the highest levels of the Federal Government. Ultimately his father risks everything to protect Alton and help fulfill a destiny that could change the world forever, in this genre–defying film as supernatural as it is intimately human.